| Kidepo Valley National Park (Karamoja – NE Uganda) | 1,442 km² | Remote wilderness, savanna plains, rugged mountains | Game drives, cultural visits (Karamojong), wilderness safaris | Lions, cheetahs, elephants, buffalo, giraffes | ~475 species |
| Murchison Falls National Park (NW Uganda) | ~3,893 km² | Nile River, dramatic waterfall, savanna & forest | Boat cruise to falls, game drives, chimp tracking | Elephants, lions, giraffes, hippos, crocodiles | ~450 species |
| Queen Elizabeth National Park (Western Uganda) | 1,978 km² | Kazinga Channel, crater lakes, savanna | Boat safaris, chimp tracking, tree-climbing lions | Elephants, lions, hippos, buffalo, leopards | 600+ species |
| Bwindi Impenetrable National Park (SW Uganda) | ~331 km² | Dense rainforest, UNESCO site, gorilla habitat | Gorilla trekking, forest walks | Mountain gorillas, forest elephants, monkeys | 350+ species |
| Kibale National Park (Western Uganda) | ~795 km² | Tropical rainforest, primate capital | Chimpanzee tracking, primate walks | Chimpanzees, 13 primate species | ~375 species |
| Lake Mburo National Park (Western Uganda) | ~260–370 km² | Savannah, lakes, acacia woodland | Walking safaris, horseback safaris, cycling | Zebras, impalas, buffalo, leopards | ~350 species |
| Semuliki National Park (Western Uganda) | ~220 km² | Lowland rainforest, hot springs | Birding, forest walks, hot spring visits | Primates, forest mammals | 400+ species |
| Mgahinga Gorilla National Park (SW Uganda) | ~33.7 km² | Virunga volcanoes, bamboo forest | Gorilla trekking, golden monkey tracking, volcano hiking | Gorillas, golden monkeys | Rich montane birdlife |
| Rwenzori Mountains National Park (Western Uganda) | ~996 km² | Snow-capped mountains, glaciers | Mountain climbing, hiking | Unique alpine fauna | Albertine Rift endemics |
| Mount Elgon National Park (Eastern Uganda) | ~1,279 km² | Extinct volcano, largest caldera | Hiking, cave exploration, waterfalls | Elephants, antelopes | 300+ species |